Identifying target populations for screening or not screening using logic regression

Identifying target populations for screening or not screening using logic regression.

Colorectal cancer remains a significant public health concern despite the fact that effective screening procedures exist and that the disease is treatable when detected at early stages. Numerous risk factors for colon cancer have been identified, but none are very predictive alone. We sought to determine whether there are certain combinations of risk factors that distinguish well between cases ...

New Platforms For Drug Screening And Toxicology: Necessity Or Need?

The liver is the largest internal organ in the human body that is responsible for more than 500 vital functions, including biosynthesis of major plasma proteins, immunity against infectious pathogens, balancing energy metabolism and xenobiotics biotransformation (1). One of the main functions of the liver is an important role in drug metabolism (2). Since developing new drug compounds into mark...

Breast screening: the facts--or maybe not.

Screening of Eleven Festuca arundinaceaNative Populations for NaCl Tolerance in Order to Use in Green Space

In the turfgrass industry, the need for salinity tolerant turfgrasses is increasing because of the increased use of saline and non-potable water. Greenhouse container experiments were conducted to determine the relative salinity tolerance and growth responses of eleven native populations of tall fescue (Festuca arundinacea Schrub) (TF), including: Semirom, Mashhad, Sanandaj, Yasuj, Yazd Abad, D...

Virtual Target Screening: Validation Using Kinase Inhibitors

Computational methods involving virtual screening could potentially be employed to discover new biomolecular targets for an individual molecule of interest (MOI). However, existing scoring functions may not accurately differentiate proteins to which the MOI binds from a larger set of macromolecules in a protein structural database. An MOI will most likely have varying degrees of predicted bindi...